米国における、小児のスティーブンス・ジョンソン症候群と中毒性表皮壊死融解症の疫学を推定した論文がPediatric Dermatologyに掲載されました。

Abstract

Although Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious, life-threatening reactions to drug therapies, no efforts have been made to investigate the comprehensive change in epidemiology with respect to age, sex, and race and ethnicity in children. The risk of death was 0.3% to 1.5%, and the highest hospitalization rates were in children 15 to 19 years of age, boys, and black children. The highest proportions of hospitalizations were children with very low household income, those with private insurance, and those treated at large urban teaching hospitals in the West. A significant winter-autumn predominance was observed.

Okubo Y, Nochioka K, Testa MA. Nationwide Survey of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Children in the United States. Pediatr Dermatol. 2017 Mar;34(2):206-208. doi: 10.1111/pde.13050. Epub 2016 Dec 19. PMID: 27990674.